

The Zebra ZD420t-HC is the healthcare version of Zebra's previous-generation 4-inch ZD420t thermal transfer desktop printer – now succeeded by the ZD421-HC and still a dependable choice for lab and specimen, blood and IV bag, pharmacy, asset and patient record labels and patient ID wristbands. It takes 74 m and 300 m ribbon rolls for durable, smudge-proof labels on paper and synthetic materials and prints sharp 203 dpi labels up to 104 mm wide at up to 152 mm/s, with ZPL and EPL support and Link-OS management. Disinfectant-ready plastics and a sealed button interface withstand constant cleaning, and the IEC 60601-1 compliant power supply is approved for use in healthcare facilities. This version, ZD42H42-T0EW02EZ, combines USB with a factory-installed dual-band Wi-Fi 5 (802.11ac) + Bluetooth 4.1 radio; the power supply, EU and UK power cords and a USB cable are included, so it is ready to print as soon as you add labels and a ribbon.
📦 What's in the box – ZD42H42-T0EW02EZ
- ✅ Zebra ZD420t-HC printer – White, USB, Wi-Fi 5 + BT 4.1
- ✅ Power supply – IEC 60601-1 certified healthcare power supply, 100–240 V
- ✅ Power cords – EU (Schuko) and UK (type G) plugs – use the one for your country
- ✅ USB cable – USB A to B, for connecting to your PC
- ✅ Manuals CD – drivers and documentation
- ✅ Setup guide
- ❌ Labels – NOT included
- ❌ Thermal transfer ribbon – NOT included
✅ Ready to print out of the box – power supply, power cords and USB cable are included; you only need labels and a ribbon.
💡 Useful extras: matching Zebra labels (Zebra Z-Select 2000T 102 × 64 mm or Zebra Z-Ultimate 3000T 76 × 51 mm); genuine Zebra ribbons (Zebra 2300 110 mm × 74 m or Zebra 2300 110 mm × 300 m); a field-installable cutter or label dispenser (Zebra P1080383-228 or Zebra P1080383-018); a serial (RS-232) module (Zebra P1080383-443); the battery base with battery for cart-based printing (Zebra P1080383-600 + Zebra P1080383-603).
Key Features
- Ribbon rolls for the lowest cost per label – takes economical 300 m Zebra ribbons (1:4 ribbon-to-media ratio) or compact 74 m ribbons, 33.8 to 109.2 mm wide, for durable labels on paper and synthetic media.
- Easy to operate – five status icons (status, pause, data, supplies, network) and a three-button interface show at a glance what the printer needs; the OpenACCESS design makes loading media quick.
- Handles virtually any media – roll-fed or fanfold labels, tags and continuous receipt paper, plus patient wristbands from 15 mm to 118 mm wide, with a movable black-mark sensor and a multi-position gap sensor.
- Wi-Fi 5 + Bluetooth 4.1 – factory-installed dual-band 802.11ac dual radio for wireless network printing and printing from Android, iOS and Windows devices; a serial (RS-232) or Ethernet module can be added on site.
- Fits into your existing fleet – supports ZPL II and EPL 2 plus many non-Zebra printer languages, so it can replace older Zebra GK-series or competitor printers without changing your label formats.
- Link-OS management – monitor and manage one printer or your whole fleet from a single location; tap an NFC phone on the Print Touch tag for Zebra's how-to videos; 512 MB flash, 256 MB SDRAM and a real-time clock.
- Upgrade on site – field-installable cutter or label dispenser, serial or Ethernet module, an attached battery base with 2750 mAh battery for cart-based printing and the ZKDU keyboard display for stand-alone use.
- Built for healthcare – disinfectant-ready, wipeable white plastics and a sealed button interface make the printer easy to clean and help prevent the spread of germs; the power supply is IEC 60601-1 compliant.
- Previous generation – successor ZD421-HC – the newer ZD421-HC is 30% more powerful and adds Wi-Fi 6, a UV-resistant housing and PrintSecure; compare all versions in the table below.
Ideal Applications
- Pharmacy – prescription and medication labels
- Laboratory – lab and specimen labels for sample tubes and containers
- Patient identification – patient ID wristbands and patient record labels
- Blood bank and wards – blood and IV bag labels
- Hospital administration and sterile services – asset, file and instrument tray labels
All ZD421-HC Versions
The highlighted row is the version you are currently viewing.
| Part Number | Model | Print Method | Resolution | Connectivity | |
|---|---|---|---|---|---|
| ZD4AH42-D0EE00EZ | ZD421-HC | Direct thermal | 203 dpi | USB, Ethernet, BLE | View product |
| ZD4AH42-D0EX02EZ | ZD421-HC | Direct thermal | 203 dpi | USB, Wi-Fi 6 + BT 5.3 | View product |
| ZD4AH43-D0EE00EZ | ZD421-HC | Direct thermal | 300 dpi | USB, Ethernet, BLE | View product |
| ZD4AH42-30EE00EZ | ZD421-HC | Thermal transfer | 203 dpi | USB, Ethernet, BLE | View product |
| ZD4AH43-30EE00EZ | ZD421-HC | Thermal transfer | 300 dpi | USB, Ethernet, BLE | View product |
| ZD4AH42-C0EE00EZ | ZD421-HC | Ribbon cartridge | 203 dpi | USB, Ethernet, BLE | View product |
| ZD4AH43-C0EE00EZ | ZD421-HC | Ribbon cartridge | 300 dpi | USB, Ethernet, BLE | View product |
| ZD42H42-T0EW02EZ (this version) | ZD420-HC (previous generation) | Thermal transfer | 203 dpi | USB, Wi-Fi 5 + BT 4.1 | Viewing |
Technical Specifications
| Part Number | ZD42H42-T0EW02EZ |
|---|---|
| Model | Zebra ZD420t-HC (ZD420-HC healthcare, previous generation – successor: ZD421-HC) |
| Printer Type | 4-inch desktop label printer – thermal transfer, 74 m / 300 m ribbon roll (ZD400 Series, healthcare) |
| Print Method | Thermal transfer and direct thermal |
| Resolution | 203 dpi (8 dots/mm) |
| Print Speed | Up to 152 mm/s (6 in/s) |
| Max. Print Width | 104 mm |
| Media Width | 15 mm to 118 mm |
| Label Length | 6.4 mm to 991 mm |
| Roll Diameter | Max. 127 mm (5.0 in) outer diameter |
| Core Size | 12.7 mm (0.5 in) and 25.4 mm (1 in) standard; 38.1 / 50.8 / 76.2 mm with optional core adapters |
| Media Thickness | 0.08 mm to 0.19 mm |
| Media Type | Roll-fed or fanfold, die-cut or continuous labels with or without black mark, tag stock, continuous receipt paper, wristbands |
| Sensors | Full-width movable reflective / black-mark sensor; multi-position transmissive / gap sensor; head-up sensor |
| Ribbon | Zebra 74 m (12.7 mm core, OD 34 mm, 1:1 ribbon-to-media) or 300 m (25.4 mm core, OD 66 mm, 1:4); width 33.8–109.2 mm; ink side out |
| Interfaces | USB 2.0 (type B); field-installable RS-232 serial (DB-9) or Ethernet 10/100 module |
| Wireless | Dual-band Wi-Fi 5 (802.11ac) + Bluetooth 4.1 dual radio, factory-installed |
| NFC | Print Touch (NFC) tag – tap to open Zebra help pages and videos |
| Memory | 512 MB flash, 256 MB SDRAM (64 MB / 8 MB user available); real-time clock |
| Printer Languages | ZPL II, EPL 2, EPL Line Mode, XML, ZBI; Link-OS |
| Fonts / Character Sets | 16 resident expandable ZPL II bitmap fonts, 2 scalable ZPL fonts, 5 EPL2 fonts, native OpenType support, Unicode |
| Barcodes | 1D: Code 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A/E, EAN-8/13 (+2/+5), Plessey, Postnet, 2-of-5 variants, Logmars, MSI, Codabar, Planet; 2D: Codablock, PDF417, Code 49, Data Matrix, MaxiCode, QR Code, MicroPDF, Aztec |
| Display | 5 status icons, 3-button user interface (no LCD) |
| Media Handling | Tear-off standard; field-installable cutter or label dispenser (peeler with label-present sensor) |
| Options | Serial and Ethernet modules; attached battery base + 2750 mAh battery; ZKDU keyboard display unit; core adapters |
| Drivers & Software | Link-OS, ZebraDesigner, Zebra Setup Utilities, Windows drivers |
| Power Supply | IEC 60601-1 compliant healthcare power supply, 100–240 V AC, 50–60 Hz, PFC; ENERGY STAR; optional 2750 mAh battery |
| Dimensions (W × D × H) | 202 × 267 × 192 mm |
| Weight | 2.4 kg |
| Color | White |
| Housing | Healthcare: disinfectant-ready, wipeable plastics; sealed button interface |
| Operating Temperature | 4.4 °C to 41 °C |
| Storage Temperature | −40 °C to 60 °C |
| Humidity | 10–90% non-condensing (storage 5–95%) |
| Certifications | IEC 60950-1, EN 55022 Class B, EN 55024, EN 61000-3-2/-3-3, EN 300 328, EN 301 893, CE, ENERGY STAR; power supply IEC 60601-1 |
| Warranty | 24 months |
| In the Box | Zebra ZD420t-HC printer (USB, Wi-Fi 5 802.11ac + Bluetooth 4.1; white healthcare housing), IEC 60601-1 healthcare power supply, power cords EU + UK, USB cable, driver / documentation CD, quick start guide – labels and ribbon NOT included |
Which ZD421-HC should you choose? The ZD421d-HC (direct thermal) needs no ribbon and suits wristbands, specimen and short-life labels; the ZD421t-HC uses 74 m or 300 m ribbon rolls for durable labels at the lowest cost per label; the ZD421c-HC loads Zebra ribbon cartridges in seconds – ideal on busy wards and in labs. 203 dpi suits most barcodes and labels, while 300 dpi gives crisper small text and tiny 2D codes on specimen tubes. Ethernet versions connect to the hospital network by cable, the Wi-Fi 6 version wirelessly; the ZD420t-HC is the previous-generation thermal transfer model with Wi-Fi 5. Compare other models in our Desktop Label Printers collection or contact our team for volume pricing.
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